Creatinine is a by product of muscle contractions that is excreted and removed from the body through urine. When creatinine phosphate is broken down as the muscles work, it results in the formation of Creatinine.
Creatinine is hardly reabsorbed back into the body if it is at all. The kidneys are responsible for the filtration of Creatinine from the blood. Creatinine is filtered from the body through glomerular filtration. In the case that a person’s kidneys are not properly functioning, the Creatinine levels in the blood will be high and these levels can be measured. When the kidneys are functioning perfectly Creatinine will be successfully filtered out of the body and excreted in the urine. Therefore the Creatinine levels in the urine are normally high.
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